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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.513057761278
5 / 7     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.330471165208
13 / 21     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.197499420491
0 / 2     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.166711965932
2 / 1     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.146856850103
9 / 1     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.146856850103
0 / 5     
Tyrosine-protein kinase FYN FYN P06241 CHEMBL1841 Kinase 0.146856850103
0 / 1     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.146856850103
0 / 6     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.146856850103
0 / 1     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.146856850103
0 / 4     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.146856850103
0 / 4     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.146856850103
0 / 1     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.146856850103
0 / 3     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.146856850103
0 / 1     
Dynamin-1 DNM1 Q05193 CHEMBL4958 Enzyme 0.146856850103
0 / 10     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0952559184207
3 / 1     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0849737018175
0 / 4     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0849737018175
0 / 4     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.0849737018175
4 / 4     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0743164735672
0 / 3     
3-phosphoinositide dependent protein kinase-1 PDPK1 O15530 CHEMBL2534 Kinase 0.0649510872641
1 / 0     
Trace amine-associated receptor 1 (by homology) TAAR1 Q96RJ0 CHEMBL5857 Family A G protein-coupled receptor 0.0649510872641
4 / 0     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.0544879468076
1 / 0     
High-affinity choline transporter (by homology) SLC5A7 Q9GZV3 CHEMBL4507 Electrochemical transporter 0.0544879468076
0 / 1     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0544879468076
0 / 1     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.0544879468076
0 / 1     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.0544879468076
0 / 1     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0544879468076
0 / 1     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.0544879468076
0 / 1     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0544879468076
0 / 1     
Serotonin transporter (by homology) SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0544879468076
4 / 0     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.0544879468076
8 / 0     
Phospholipase A2 group IIA PLA2G2A P14555 CHEMBL3474 Enzyme 0.0544879468076
0 / 1     
Phospholipase A2 group 1B PLA2G1B P04054 CHEMBL4426 Enzyme 0.0544879468076
0 / 1     
Nischarin NISCH Q9Y2I1 CHEMBL3923 Other cytosolic protein 0.0443083186041
1 / 0     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.0443083186041
6 / 0     
Lysine-specific histone demethylase 1 KDM1A O60341 CHEMBL6136 Eraser 0.033970689612
2 / 0     
Neuronal acetylcholine receptor; alpha2/beta4 CHRNB4 CHRNA2 P30926 Q15822 CHEMBL2109230 Unclassified 0.033970689612
1 / 1     
Neuronal acetylcholine receptor; alpha3/beta2 CHRNA3 CHRNB2 P32297 P17787 CHEMBL2109234 Ligand-gated ion channel 0.033970689612
1 / 1     
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.033970689612
3 / 3     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.033970689612
3 / 0     
Anti-estrogen binding site (AEBS) EBP Q15125 CHEMBL4931 Enzyme 0.033970689612
0 / 1     
Alcohol dehydrogenase alpha chain ADH1A P07327 CHEMBL1970 Oxidoreductase 0.033970689612
0 / 1     
Alcohol dehydrogenase gamma chain ADH1C P00326 CHEMBL3285 Oxidoreductase 0.033970689612
0 / 1     
Phenylethanolamine N-methyltransferase PNMT P11086 CHEMBL4617 Enzyme 0.0238327432783
1 / 0     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.0238327432783
0 / 2     
Mu opioid receptor (by homology) OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0238327432783
0 / 4     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0238327432783
2 / 0     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0238327432783
1 / 0     
Polyadenylate-binding protein 1 PABPC1 P11940 CHEMBL1293286 Unclassified protein 0.0238327432783
0 / 1     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0238327432783
0 / 1     
Solute carrier family 22 member 2 SLC22A2 O15244 CHEMBL1743122 Electrochemical transporter 0.0238327432783
1 / 0     
Multidrug and toxin extrusion protein 1 SLC47A1 Q96FL8 CHEMBL1743126 Electrochemical transporter 0.0238327432783
1 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.